Abstract Background STAT3 hyper-IgE syndrome (STAT3-HIES) is a rare primary immunodeficiency that clinically overlaps with atopic dermatitis.In addition to eczema, elevated serum-IgE, and recurrent infections, STAT3-HIES patients suffer from characteristic facies, midline defects, and retained primary teeth.To optimize dental management we assessed
Prolonging dairy cattle longevity is regarded as one of the options to contribute to a more sustainable milk production.Cattle longevity is a direct result from culling decisions, which is primarily driven by economic considerations.As a consequence, at the herd level, cattle longevity can have effects on the efficiency of dairy production.This stu
The clinical trial of allogenic mesenchymal Protection stem cells (MSCs) transplantation for refractory SLE patients has shown significant safety and efficacy profiles.However, the optimum frequency of the MSCs transplantation (MSCT) is unknown.This study was undertaken to observe whether double transplantations of MSCs is superior to single transp
Abstract Background The human genome encodes over 14,000 pseudogenes that Sexual Health are evolutionary relics of protein-coding genes and commonly considered as nonfunctional.Emerging evidence suggests that some pseudogenes may exert important functions.However, to what extent human pseudogenes are functionally relevant remains unclear.There has